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KMID : 0614620160680040175
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Korean Journal of Gastroenterology
2016 Volume.68 No. 4 p.175 ~ p.178
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Gastric Mucosa-associated Lymphoid Tissue Lymphoma Based on Outcome of Domestic Treatment
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Jung Jin-Tae
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Abstract
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Gastric mucosa-associated lymphoid tissue (MALT) lymphoma is associated with Helicobacter pylori infection. H. pylori eradication can be performed as a primary therapy regardless of H. pylori status. In Korea, six articles were published about low-grade gastric MALT lymphoma with H. pylori. Complete regression rate after H. pylori eradication is reported at 74.5% to 94.4%. Radiotherapy results in favorable clinical long-term outcomes in patients with early-stage gastric MALT lymphoma who fail H. pylori eradication therapy and those who are H. pylori negative. Chemotherapy could be reserved for patients with metastatic or high-grade lymphoma. In gastric MALT lymphoma, patients with polypoid type on initial endoscopy had a higher likelihood of recurrence than those with diffuse infiltration or ulceration types. The depth of invasion, location of lesions, and chromosomal abnormality with t(11;18) together are predictive factors for failure to remission by H. pylori eradication.
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KEYWORD
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Mucosa-associated lymphoid tissue, Stomach, Therapy
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